Landmark Research Journals of Medicine and Medical Sciences 
June 2017 Vol. 4(2), pp. 016-024
Copyright © 2017 Landmark Research Journals

Review

 

Ethnobotanical uses, phytochemical and pharmacological profiles, and toxicity of Cassia alata L. An overview.

1Olivier Tene Tcheghebe, 2Viviane Raïssa Sipowo Tala, 3Francis Ngouafong Tatong, 4Gabriel Kamsu Tchuente

 

1Inorganic Chemistry Department, Faculty of Science, P.O. Box 812, University of Yaounde I.

2 Faculty of Health Sciences, P.O. Box 208, Université des montagnes, Bangangté, Cameroon

3Chemistry Department, University of Dschang, P.O Box 67 Dschang; West Region, Cameroon.

4Biochemistry Department, University of Dschang, P.O Box 67 Dschang; West Region, Cameroon.

*Corresponding Author's Email: tetcholi@yahoo.com

Accepted 26 May, 2017

ABSTRACT

There are very ancient references for utilization of herbs, plants and other natural substances in clinical treatments. This knowledge is common among the people living in rural areas of developing countries. Cassia alata is one of these plants largely used by traditional health practitioners with a proved effectiveness. In the folkloric medicine, this plant is involved in curing asthma, constipation, haemorrhoids, intestinal parasitosis, skin problems, jaundice and hepatitis, typhoid, diabetes and breast cancers. Pharmacological tests undertaken on this plant’s extracts have showed its antimalarial, anti-cancer and antitumor, anti-inflammatory, anthelmintic, antioxidant, hepatoprotective and hepatocurative, antibacterial and antifungal, cardioprotective, anti-diabetic and antihyperlipidemic, bronchorelaxant and antiviral activities. Some bioactive components such as quinones and anthraquinones, tannins, flavonoids, saponins, alkaloids, steroids, cardenolides, resins, phenols and triterpenoid, significantly present in the plant’s extracts support its pharmacological profile and its uses in traditional medicine. More interesting yet, it has been scientifically proved that Cassia alata extract is safe till a dose of 16875 mg/kg body weight.  This review study is an effort to give a detailed survey of the literature on the ethnobotanical uses, phytochemical and pharmacological profiles, as well as the toxicity of Cassia alata.

Keywords:  Cassia alata, ethnobotanical uses, phytochemical, pharmacological, toxicity

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